Key takeaway
Acamprosate can help reduce alcohol craving after detox, but diarrhea, nausea, and mood changes are among reported side effects. Kidney disease may require dose changes or avoidance. Call or text (800) 653-9376 for help finding alcohol treatment that includes medication options.
Last updated: Wed Oct 07 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
Acamprosate (brand Campral) is an FDA-approved medication that can support abstinence after alcohol detox. Side effects are usually manageable, but they are not rare, and kidney function matters.
Call 911 for emergencies. Call or text 988 for a crisis.
Common effects people ask about
Diarrhea is frequently discussed. Nausea, abdominal discomfort, appetite change, anxiety, depressed mood, dizziness, and itching also appear in patient counseling materials. Timing and intensity vary.
Serious warnings to take seriously
Suicidal thoughts and worsening depression can occur with alcohol use disorder and with some medications - report mood changes promptly. Severe allergic reactions need emergency care. Do not start or stop acamprosate based on a forum anecdote.
Not a detox drug
Acamprosate does not make alcohol withdrawal safe. If you are a heavy daily drinker, get medical detox guidance first. Sibling: naltrexone for alcohol, Campral.
Broker filter
A center that pushes residential care while refusing to discuss FDA-approved alcohol medications is not offering a complete options set.
Next step
Review labeling with your clinician, search FindTreatment.gov, or call or text (800) 653-9376.
Additional Resources
Sources cited on this page:
- NIDA: Principles of Drug Addiction Treatment
- NIAAA: Treatment for Alcohol Problems
- DailyMed: Acamprosate labeling
- SAMHSA FindTreatment.gov
- 988 Suicide & Crisis Lifeline
Common Questions
What are common acamprosate side effects?
Diarrhea, nausea, gas, appetite changes, anxiety, depression, dizziness, and itching are among commonly discussed effects. Ask your clinician what to expect on your dose.
Is acamprosate the same as Campral?
Campral is a brand name for acamprosate. Generics may be used. See also Campral.
Who should not take acamprosate?
Severe kidney impairment is a key caution. Always review kidney function, other medicines, and pregnancy plans with a clinician.
Does acamprosate treat withdrawal?
No. It is used after acute withdrawal is managed, to support abstinence. Dangerous alcohol withdrawal needs medical detox first.
What if side effects are severe?
Seek urgent care for severe allergic reactions, suicidal thoughts, or symptoms your clinician told you to treat as emergencies. Call or text 988 for a crisis.