Naltrexone for Alcohol Use Disorder

How naltrexone is used for alcohol use disorder, oral vs injectable options, side effects, and when it is not appropriate.

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Key takeaway

Naltrexone can reduce heavy drinking and support recovery from alcohol use disorder when used with counseling. It is not for people who currently need opioids. Call or text (800) 653-9376 for help finding alcohol treatment that includes medication options.

Last updated: Wed Oct 07 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Naltrexone is one of the FDA-approved medicines for alcohol use disorder. It can reduce the rewarding effects of drinking and support fewer heavy-drinking days when paired with counseling.

Call 911 for emergencies. Call or text 988 for a crisis.

Oral vs injectable

Daily tablets and monthly extended-release injections are both used. Choice depends on adherence, liver history, opioid use, and preference. Sibling: naltrexone side effects, naltrexone / Vivitrol.

Opioid caution

If you take opioids for pain or have opioid use disorder, naltrexone planning must be explicit. Starting too early can precipitate withdrawal.

Not a detox substitute

Seizures and DTs are medical emergencies. Stabilize withdrawal first when needed, then discuss naltrexone.

Broker filter

A center that only offers a non-medication residential pitch for alcohol use disorder is not describing the full evidence-based menu.

Next step

Clinician visit, FindTreatment.gov, or call or text (800) 653-9376.

Additional Resources

Sources cited on this page:

Common Questions

Does naltrexone help with alcohol?

Yes. Oral naltrexone and extended-release injectable naltrexone are used for alcohol use disorder as part of a broader treatment plan.

Is Vivitrol the same thing?

Vivitrol is an extended-release injectable naltrexone product. Oral tablets are a different dosing form of the same medicine class.

Can I take naltrexone if I still use opioids?

No. Naltrexone blocks opioid receptors and can precipitate withdrawal if opioids are still in your system.

What side effects should I know?

Nausea, headache, dizziness, and injection-site reactions (for the shot) are commonly discussed. See naltrexone side effects.

Does it replace detox?

No. Dangerous alcohol withdrawal still needs medical management first when indicated.