Quick answer
St. Louis recorded 388 fatal overdoses in the city in 2022, with methamphetamine among the leading causes after opioids and fentanyl. The metro has 47 treatment programs within 25 miles, 22 offering contingency management - the best-evidenced therapy for stimulant use. Call (800) 653-9376, or 988 in a crisis.
St. Louis is a fentanyl-first market, and meth rides with it: the city's own fact sheet shows 388 fatal overdoses in 2022, over 90% caused by opioids, with fentanyl dominant and cocaine, alcohol, and methamphetamine filling out the leading causes. Statewide, meth was listed as a cause in 40% of 2023 overdose deaths. The metro's treatment base is broad - 47 programs within 25 miles, 22 of them offering contingency management. Here is the picture and the way in.
What the metro's treatment map holds
A SAMHSA locator search centered on the city at a 25-mile radius returns 47 substance use treatment programs, covering both the city and inner St. Louis County:
- 44 offer outpatient care and 38 run intensive outpatient (IOP) - the starting levels for most people
- 9 offer residential care and 11 offer detoxification for people who need distance from their using environment or monitoring through early withdrawal
- 22 report contingency management, 40 offer cognitive behavioral therapy, and 46 offer motivational interviewing
- 16 run the Matrix Model, a structured outpatient protocol built for stimulant users
- 39 offer telehealth, 30 use buprenorphine for co-occurring opioid dependence, 34 accept Medicaid, and 25 report a sliding fee scale
Metro programs such as Birch Tree Recovery on Ladue Road appear in the results, but openings turn over quickly - confirm admissions by phone rather than trusting any directory as a live list.
How meth treatment works
There is no FDA-approved medication for methamphetamine use disorder - the federal HHS contingency management review states that no pharmacotherapy has been approved for any stimulant use disorder. Treatment is behavioral:
- Contingency management (CM): small, non-cash rewards - vouchers or prize draws - for verified drug-free tests. Federal reviews rate it the most effective available treatment for stimulant use disorder; 22 metro programs report offering it.
- Cognitive behavioral therapy: building awareness of triggers and rehearsing responses that do not lead back to use.
- The Matrix Model: a 16-week structured outpatient program combining individual and group therapy, family education, drug testing, and self-help participation.
Because nothing pharmacological stabilizes the first weeks, contact density is the lever that matters. An IOP schedule of several sessions per week gives a stronger start than one weekly appointment.
What the local numbers show
- St. Louis City recorded 314 resident drug overdose deaths in 2022 (up 11% from 2021), and 388 fatal overdoses occurred in the city that year, per the Missouri DHSS fact sheet. Over 90% were caused by opioids, with fentanyl and its metabolites the most common substances; cocaine and alcohol came next, with methamphetamine also among the top substances causing death.
- St. Louis County recorded 394 resident overdose deaths in 2022 (down 5%) and 331 fatal overdoses occurring in the county, nearly 90% caused by opioids, with stimulants such as cocaine and methamphetamine the next leading causes.
- Statewide, Missouri's SUDORS state fact sheet lists fentanyl as a cause in 72.1% of deaths, methamphetamine in 40.0%, and cocaine in 19.0%.
- The city's population is about 280,000 (Census Bureau 2024 estimate) - which makes 388 overdose deaths in one year an extraordinary per-capita burden; CDC-based county rates put St. Louis city at the top of Missouri.
The practical read: in St. Louis, a meth-focused treatment plan has to assume fentanyl exposure. Naloxone belongs in the plan regardless of the drug someone entered for.
When stopping meth needs help
Meth withdrawal is rarely a medical emergency the way alcohol or benzodiazepine withdrawal can be. It is a long crash - exhaustion, disrupted sleep, returning appetite, and cravings concentrated in the first weeks. Two complications call for professional attention:
- Severe depression after last use carries suicide risk. Call or text 988 if mood collapses or thoughts of self-harm appear.
- Meth-induced psychosis - paranoia, hallucinations, agitation - usually eases within weeks off the drug but can be dangerous while active. Call 911 in an emergency.
Paying for care in St. Louis
MO HealthNet (Missouri Medicaid) covers behavioral health and substance abuse services for eligible members, including IOP and residential levels when medically necessary, through three statewide managed care plans: Healthy Blue, UnitedHealthcare Community Plan, and Home State Health. Missouri's 2021 expansion made adults up to 138% of the federal poverty level eligible. Twenty-five metro programs report sliding fee scales; the SAMHSA National Helpline (1-800-662-4357) can help uninsured residents find publicly funded options.
How to start today
- In a medical emergency, call 911. In a crisis or with thoughts of self-harm, call or text 988.
- Call or text (800) 653-9376 to talk options through with a treatment specialist, or use this form:
Calling is free; the referral service is paid for by treatment providers, and we check your benefits before you commit.
- Search findtreatment.gov from ZIP 63101, set the radius, and filter by level of care and payment.
- Ask about contingency management by name, and ask how the program handles fentanyl co-exposure - in this market the two drugs arrive together.
- Keep naloxone nearby. It reverses opioid overdoses, not meth - but fentanyl is what ends lives fastest in St. Louis.
Methamphetamine use disorder is treatable, and St. Louis has both the program depth and the public safety net to meet it. The first call is the one that changes the picture.
Last updated: Sun Oct 18 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
Frequently asked questions
How many meth treatment programs are near St. Louis?
The SAMHSA FindTreatment.gov locator lists 47 substance use treatment programs within 25 miles of the city. Of those, 44 offer outpatient care, 38 run intensive outpatient (IOP), 9 offer residential care, 11 offer detoxification, and 22 report offering contingency management - the behavioral treatment with the strongest evidence for stimulant use.
How does meth compare with fentanyl in St. Louis overdose deaths?
In the city's 2022 fact-sheet data, over 90% of overdose deaths were caused by opioids, with fentanyl the most common substance and cocaine and alcohol the next leading causes; methamphetamine also ranked among the top substances causing death. Statewide in 2023, methamphetamine was listed as a cause in 40% of fatal overdoses - second to fentanyl at 72.1%.
What is the difference between St. Louis City and St. Louis County for treatment?
St. Louis is an independent city, not part of St. Louis County, and the two publish separate overdose data - the city recorded 388 fatal overdoses in 2022 and the county 331, with 394 resident deaths. For treatment, the 25-mile search radius from the city covers both, so check programs on both sides; the locator is the fastest way to see what is nearby.
What treatments actually work for meth?
There is no FDA-approved medication for methamphetamine use disorder. Contingency management - non-cash rewards for verified drug-free tests - has the strongest federal evidence. Cognitive behavioral therapy (40 metro programs) and the Matrix Model (16 programs) are the other core options. Ask any program whether it runs contingency management for stimulants specifically.
Does Missouri Medicaid cover meth treatment in St. Louis?
Yes, for eligible members. MO HealthNet covers behavioral health and substance abuse services, including intensive outpatient and residential care when medically necessary, through managed care plans Healthy Blue, UnitedHealthcare Community Plan, or Home State Health. Missouri expanded Medicaid in 2021; 34 of the 47 programs in the search report accepting Medicaid and 25 report a sliding fee scale.