Brixadi vs Sublocade

How Brixadi and Sublocade compare as extended-release buprenorphine injections for opioid use disorder, including dosing intervals and practical differences.

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Key takeaway

Brixadi and Sublocade are both extended-release buprenorphine injections for opioid use disorder, with different dosing schedules and formulations. Neither replaces counseling or overdose planning. Call or text (800) 653-9376 for help finding MOUD providers.

Last updated: Wed Oct 07 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Both products deliver buprenorphine over time so people with opioid use disorder do not need a daily transmucosal dose. They are not identical products.

Call 911 for emergencies. Call or text 988 for a crisis. Carry naloxone.

Shared idea

Extended-release buprenorphine for OUD under medical supervision, usually after a transmucosal buprenorphine start per labeling.

Practical differences

Dosing interval, dose strengths, injection site rules, and REMS/pharmacy pathways differ by product. Use current FDA labeling rather than a marketing flyer.

Cost and access

Prior authorization is common. See Sublocade treatment and Sublocade cost.

Broker filter

A caller who insists only one injectable brand works for everyone is selling inventory, not matching care.

Next step

OTP or office-based MOUD clinician, FindTreatment.gov, or call or text (800) 653-9376.

Additional Resources

Sources cited on this page:

Common Questions

What is the difference between Brixadi and Sublocade?

Both are injectable extended-release buprenorphine products for OUD. They differ in approved dosing intervals, strengths, and product labeling. A clinician chooses based on your history and access.

Do I still need counseling?

Medication works best as part of a broader treatment plan that can include counseling, recovery supports, and naloxone.

Can I switch between them?

Possibly under clinical supervision. Do not self-switch or stack products.

Is this the same as Suboxone?

Suboxone is a transmucosal buprenorphine/naloxone product. Sublocade and Brixadi are long-acting injections.

What about cost?

Coverage and prior auth vary by plan. See Sublocade cost for one product's pricing questions.